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AB-1005 gene therapy placed on fast track by regulators in US, UK

AskBio’s investigational gene therapy AB-1005 has been granted fast-track designation for Parkinson’s disease by the U.S. Food and Drug Administration (FDA), and innovation passport designation by the regulatory agency in the U.K. These…

Parkinson’s disease fundraisers can actually be fun, I’ve found

It’s that time of year again: time for our annual Walk for Parkinson’s. I hate asking people for money, even for such a worthwhile cause as our local Parkinson’s Society here in Ontario,…

Low-dose TED-A9 cell therapy eases Parkinson’s motor symptoms: Study

The first three Parkinson’s disease patients who received a low dose of TED-A9, an investigational stem cell-based therapy being developed by S.Biomedics, saw reduced motor symptoms after a year without any reported side…

Scientists ID key regulator that helps prevent toxic protein clumps

Scientists have discovered a new regulator — called NHR-49 — that may shed light and open potential new therapeutic avenues to prevent the formation of toxic protein clumps, a hallmark of aging-related diseases,…

Anew Medical to advance development of Klotho gene therapy

Anew Medical said it will advance clinical development of its Klotho gene therapy program to prevent or stop the progression of neurodegenerative diseases, including Parkinson’s disease. Initial data suggest that maintaining high levels…

Blood test could predict Parkinson’s seven years before symptoms

Scientists have developed a simple blood test that uses artificial intelligence (AI) to predict Parkinson’s up to seven years before the onset of symptoms.

Erasing ‚bad memories‘ to improve long term Parkinson’s disease treatment

By prohibiting the Activin A protein from functioning, researchers were able to halt the development of dyskinesia symptoms and effectively erase the brain’s ‚bad memory‘ response to L-DOPA treatments.

Dopamine linked to mentalizing abilities

A link between the neurotransmitter dopamine and the mentalizing abilities of healthy people has been identified.

Caffeine affects brain dopamine function in patients with Parkinson’s disease

Regular high caffeine consumption affects dopamine function in patients with Parkinson’s disease, shows a new international study. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging results.

Smartwatches offer window into Parkinson’s disease progression

New research adds to growing evidence that widely used and user-friendly consumer devices, in this instance an Apple Watch paired with an iPhone, can detect changes in Parkinson’s symptoms over time in individuals…